ALL ABOUT MS Pregnancy
and MS (Part 14)
Therapy
of MS during pregnancy
During pregnancy,
corticosteroid therapy should be administered only in case of severe MS
deterioration. The use of this therapy should be avoided during the first three
months of pregnancy due to an increased risk of damage to the fetus. It is
considered to be the safest for the fetus to apply short-term
methylprednisolone for the treatment of MS worsening during pregnancy. In
pregnancy, the use of mitoxantrone and other cytostatics is contraindicated.
For interferon beta, there is no evidence of adverse effects on the fetus, and
for this reason, it should not be interrupted by pregnancy if the patient was
in the onset of the pregnancy at the very beginning of the treatment. There are
a large number of women who have had normal pregnancy, the birth and
development of the child and have received interferon beta during the first few
months of pregnancy. However, it is known that this medicine increases the risk
of spontaneous abortion, so this therapy should definitely be discontinued
during pregnancy. In any case, therapy with interferon beta or glatiramer
acetate should be discontinued if pregnancy is planned due to an unknown effect
on the fetus.
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